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How is muscle mass regulated? | Nutritionist explains | Myprotein

Jul 31, 2026
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How is muscle mass regulated? Learn how muscle protein synthesis and muscle protein breakdown determine whether you build or lose muscle, why resistance training is the biggest driver of muscle growth, and the essential role of protein and leucine. In this video, expert nutritionist Dr Richie Kirwan explains the science of muscle regulation, breaking down how your body is constantly balancing muscle protein synthesis and muscle protein breakdown, and what you can do to shift that balance in favour of muscle growth. Key Facts: Muscle mass is regulated by the balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB). Resistance training is the most powerful stimulus for increasing muscle protein synthesis. Consuming enough high-quality protein provides the essential amino acids needed to repair and build muscle. Leucine, one of the three branched-chain amino acids (BCAAs), plays a key role in triggering muscle protein synthesis. Building muscle requires both consistent resistance training and sufficient daily protein intake. FAQ: Q: What determines whether you gain or lose muscle? A: Muscle growth occurs when muscle protein synthesis exceeds muscle protein breakdown over time. Q: What is the most important factor for building muscle?

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