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The Science Behind Ozempic & Mounjaro | Nutritionist Explains | Myprotein

Oct 20, 2026
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How do GLP-1 weight loss drugs like Ozempic, Wegovy and Mounjaro actually work? These medications can produce significant weight loss by reducing hunger, controlling appetite and helping people feel fuller for longer. In this video, expert nutritionist Dr Richie Kirwan explains the science behind GLP-1 medications, how semaglutide and tirzepatide work, and why these weight loss injections have produced such impressive results in clinical trials. Key Facts: GLP-1 stands for glucagon-like peptide-1, a hormone naturally released by your gut after eating. GLP-1 helps stimulate insulin release and sends signals to your brain that influence hunger and fullness. Your body's natural GLP-1 is broken down within minutes, while medications such as semaglutide are designed to remain active much longer. Semaglutide, the active ingredient in Ozempic and Wegovy, mimics the effects of GLP-1. Tirzepatide, the active ingredient in Mounjaro, acts on both GLP-1 and GIP receptors. These medications help people feel less hungry, experience fewer cravings and become satisfied with smaller amounts of food. In major clinical trials, participants lost approximately 15% of their body weight with semaglutide and over 20% with higher doses of tirzepatide over roughly 18 months. These results represent a major development in obesity treatment, with weight loss approaching levels previously associated primarily with bariatric surgery. FAQ: Q: What does GLP-1 stand for? A: GLP-1 stands for glucagon-like peptide-1. It's a hormone naturally released by your gut after eating that helps regulate blood sugar and appetite. Q: How does Ozempic help you lose weight? A: Ozempic contains semaglutide, which mimics GLP-1 and helps reduce hunger and food intake, making it easier to consume fewer calories. Q: What's the difference between Ozempic and Mounjaro? A: Ozempic contains semaglutide, which acts on GLP-1 receptors. Mounjaro contains tirzepatide, which acts on both GLP-1 and GIP receptors. Q: How much weight can you lose on GLP-1 medications? A: Major clinical trials have reported average weight reductions of around 15% with semaglutide and over 20% with higher-dose tirzepatide, although individual results vary. Q: Why do GLP-1 medications reduce appetite? A: These medications act on pathways involved in appetite regulation, helping people experience less hunger, fewer cravings and greater feelings of fullness. Q: Are GLP-1 medications as effective as weight loss surgery? A: The weight loss achieved with newer medications can approach results seen with some bariatric procedures, although surgery and medication have different benefits, risks and long-term considerations. #myprotein #wheyprotein #protein #nutrition ********************************* Myprotein is Rated Excellent on Trustpilot 🔔 Subscribe to our channel: https://www.youtube.com/user/MyproteinUK?sub_confirmation=1 📲 Download the Myprotein app: https://myprotein.onelink.me/IYeO/o2erh9hb The UK & Europe's Number 1 Online Sports Nutrition Brand, Myprotein.

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