"One of the largest mitigating factors against getting traumatized is who is there for you at that particular time."
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In the preamble to the definition of PTSD, we write
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these people have been exposed to an extraordinary event that is outside of normal human experience
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So it turned out that this is not an unusual experience at all
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The trauma is not the event that happens, the trauma is how you respond to it
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The degree to which when you're traumatized, your body keeps mobilizing itself to fight
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You have all kind of immunological abnormalities, you have endocrine abnormalities, and that really devastates your health
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your physical health, at the long range of that the physical problems are longer lasting
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than the mental problems. One of the largest mitigating factors against getting traumatized is who is there for you
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at that particular time. I did the first study on Prozac for PTSD, the first study for Zoloft for PTSD, and a
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number of other conventional drugs. What we found is that it didn't work very well
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Hi, my name is Bessel van der Kolk. I'm a psychiatrist, neuroscientist, the author of the book, The Body Keeps His Core
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I got interested in trauma on my first day working at the Veterans Administration
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By the very first day that I met Vietnam veterans, I was just blown away
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These were guys who were my age, who were clearly smart and competent and had done very good things
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flying helicopters and running boats and doing good stuff in the military
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and they clearly were just a shadow of their former self. And what particularly intrigued me is that they had nightmares about what had happened
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and also that they kept referring back to their dead comrades. Their hearts seemed to be with the people who were no longer around
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and what struck me immediately is they had a very hard time connecting with new people after the war
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What also struck me is how their bodies were clearly affected by trauma
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These were guys who used to be athletic and now they were slumped over and they were uptight
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and their voices were uptight and they were sort of passive much of the time
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And then people told them something that was disappointing and they went from zero to ten
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and blew up and became extremely angry. And it was just at the time that
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that we were having two small children who were a little bit like that
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Little babies go from zero to ten, but I know that when a baby becomes very upset, within
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10 minutes you can sort of hold them and calm them down. And these soldiers were very much like little babies, except the stuff that's supposed to
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happen to allow you to not overreact to the minor things seemed to have been destroyed
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or something seems to have happened to them that made it very hard for them to modulate
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their responses to their environment. And what was also really striking is that they had a hard time being in any way meaningfully
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involved in the present. They had a hard time loving their wives and girlfriends
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They had a hard time really connecting with their kids. So something seems to have been destroyed by their capacity to engage and possibly even
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to learn new experiences. 1978 was the year that I first saw veterans, and that was also the time that my colleagues
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and I soon joined them, started to think about how is what these guys suffer from different
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from what other people who are in sexuality textbooks, because clearly they were different
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and I couldn't find a textbook to describe them. From that time that I first started to work for the VA, a group of us started to define
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what trauma is and started to define what happens to people. In the preamble to the definition of PTSD, we write, these people have been exposed to
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an extraordinary event that is outside of normal human experience. And in retrospect, that shows us how ignorant and narrow-minded we were because it turned
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out that this is not an unusual experience at all. That one out of five women in America
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has a history of sexual molestation. Even a lot of men have histories of sexual molestation
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One out of four kids get beaten very hard by their parents. One out of eight kids see
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physical fights between their parents. When we started to work with Indo City kids, the
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The amount of trauma that these kids experienced was just unspeakable. So somehow we had managed to turn a completely blind eye how what happens in people's environment
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creates the mind and creates who people become and creates certain forms of pathology
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It was a real wake-up call. And there was a lot of debate of what a trauma is to this day
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And even sometimes when I define it in the way we officially do, people still don't like
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what I say. But basically what the trauma is, is something that happens to you that makes you so upset
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that it overwhelms you. It freaks you out and you cannot, you just stand there or sit there or lie there or whatever
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and you are at a loss about to do. You feel terrible, helpless, hopeless, and you collapse
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Basically, there's an internal state of, oh my god. So it's not somebody being mean to you or nasty to you or it is really bad stuff
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But the trauma is not the event that happens. The trauma is how you respond to it
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Let me give you an example. As a medical student, I was trained to deal with all kinds of very difficult situations
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And I remember vividly during my internship that a kid was brought in, a little child
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with third degree burn wounds all over his body. But I was trained as a medical student about what to do
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So rather than freaking out, I thought, okay, I need to get my IV going, I need my fluids going
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I focused on what to do. So that exposure to these horribly burned kids was not a trauma for me because I was
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not paralyzed in my actions because I had been trained to deal with it
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And of course, that happens to policemen, that happens to people in the service, it happens
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to physicians, nurses, et cetera. It's that you get trained on what to do and not to get overwhelmed by your feelings, but
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to actually be able to continue to act and do something. And when you're traumatized, you just are unable to do anything
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It a subjective experience and what may be traumatic for you may not be traumatic for me vice versa and vice versa depending on our personality and our training An event becomes traumatic if your response is oh my God when there is nothing you can
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think of, you can do to stave off the inevitable, where you basically collapse in a state of
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confusion, maybe rage, maybe collapse, because you are unable to function in the face of
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this particular threat. An event like that may not become a trauma in the long range if at the moment that you
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collapse, other people around you come over and say, oh, I see that you're really in bad shape
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Let me help you. Let me take over for you and do things that you cannot do yourself
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And so the greatest protector against the trauma is the people around you, whether they're
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able to protect you and to do what needs to be done, or whether the people around you
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actually make it worse by continuing to do terrible things to you or blaming you for
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your responses. Trauma is actually, unlike what we first thought, extremely common
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At least one out of eight kids in America witness physical violence between their parents
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A larger number of kids get hit in very nasty ways by their own caregivers
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A very large number of people in general, but women in particular, have sexual experiences
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that were clearly unwanted and that left them helpless and befuddled, confused and enraged
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because they had no choice about what they were doing. These experiences are extremely common
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So people usually think about the military when they talk about trauma
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but I like to say somewhat unscientifically that for every soldier who gets PTSD in a war zone
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there's at least 30 children who get traumatized at home. The nature of trauma is that an experience enters
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into your ears, into your skin, into your eyes, into sensations. And it goes down into a very primitive part of your brain that automatically interprets
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what is going on. That's not your frontal lobe. What your frontal lobe, your conscious cognitive self, that is a later issue
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The first thing is a somatic response. So something happens to you, your survival brain makes the first interpretation and says
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Is this dangerous or is this safe? That decision is made for you by that primitive survival brain
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And that's what we learned a lot about when we studied trauma is the power of that primitive
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brain which occupies a very large part of our brain that really automatically makes decisions
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for us. And on the basis of the messages we get from our body, our cognition interprets in a particular
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way, depending on our prior experiences. But the message comes from our hormones and our physiological impulses that have to do
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with survival. We're talking about staying alive. And so when you're being raped or you're being beaten or you see your parents getting killed
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your body starts automatically going to a state trying to make yourself survive
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One of the states is going to fight flight, to get up and to punch people and to become
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very angry. And that's oftentimes when people are traumatized, those fight-flight responses continue to get
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activated in response to situations where people in their environment says, hey, hey
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cool, this is not so bad. But people have these automatic responses
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Or on a more primitive level even, is that people's brain shuts down and they lose track
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of themselves and they basically make themselves disappear. Very much like animals can do that also in the wild
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They can sort of collapse and play possum, as it were. And playing possum is exactly what happens to people
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Also, when you beat a kid enough, that kid starts collapsing and no longer responds to
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its environment. So it is either fight flight or collapse, none of which have anything to do with cognition
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And doing cognitive therapy with that is really a misunderstanding of what happens with traumatized people
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automatic responses and they don't have these responses because they're stupid or because
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they don't understand what's going on. Most people actually do understand that their reactions are completely out of whack
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They don't need to be told that. But because they react in such an extreme way, they feel deeply ashamed about themselves
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because they say to themselves, I'm a nut cake. I screamed at people
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I collapsed when I had to stand up for myself. And so you have these automatic responses that are not a product of your cognitive assessment
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They're a product of your animal brain trying to stay alive in the face of something that that part of your brain interprets as a life threat
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Even though the people around you by now go, this is not a life threat at all
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We come into the world being able to do what little babies can do
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And what can little babies do? They can breathe. They can sleep. They can suck
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They can feel hungry, they can poop, they can pee, they can cry, and that's about it
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So we call that the housekeeping of the body. Little babies already can do that
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And little babies, their system gets very activated, so babies will scream and they'll
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cry and it'll look catastrophic. And then the people around them pick them up and soothe them and calm that part of the
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brain down. Much of the imprint of trauma is in a very primitive survival part of your brain that's
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already in place in little babies. In fact, what the research recently has been showing, there's a little area, way, just
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way the base of your skull, periaqueductal gray, that I like to call the cockroach brain
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There's a part of you that just picks up what's dangerous and what's safe
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And now it turns out that when you're traumatized, that little part of your brain, which is usually
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very quiet for most of us, continues to just send messages to you when you're traumatized
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And so there's always this sort of message you get from deep down inside of your body
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of I'm in danger, I'm not safe. So you're always uptight, always on alert, and you spend much of your energy trying to
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suppress those feelings of fear in order not to embarrass yourself in order to be able
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to work with what you do. And so it's very primitive. that middle of the primitive part of your brain, you develop a limbic system
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And your limbic system basically creates an internal map of the world that tells you what
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out there is safe, what is dangerous. So if you say to me, boy, after this interview is over, let's go to the store and plow down
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the street and have a nice lager beer, I go like, wow, that's so cool, because I love
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that bar. And I don't love that bar. So, already in my internal mind, I have a map of what is safe and what's dangerous
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And that map is created by the experiences we have So the brain is a use organ And the brain gets formed on the basis of the experiences that we have particularly in the first few years of your life
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So if you're a little kid and you grow up in very safe surroundings
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and people are delighted to see you, and people say, isn't she cute
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Isn't she wonderful? You grow up with the sense of, I'm so cute
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and people love me because that becomes the map of your world. That's how people respond to you
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And basically that stays with you for much of the rest of your life. If you're a little kid and people say to you, as I hear all the time
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I wish you hadn't been born. I tried to abort you, but I fail
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You just really ruined my life. You just have always been pain in the ass
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That becomes your map of the world. And a little kid doesn't say when you're three years old or five years old
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Mom, you're crazy saying that about me. because a little kid doesn't have other ways of looking at the world
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So the world that you live in is the only world that it is. And if you're being treated as a difficult, unpleasant person
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that becomes your perception of yourself, I'm fundamentally a bad, defective person
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And that, people's cognition does not make that go away. People can tell you until you're ruined if it's
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oh, you're wonderful, you're terrific. I've known a whole bunch of people like that
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who were very abused and neglected as kids, who have become amazing musicians, artists, athletes
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The world adores them, and deep inside, they still feel like crap, that they're defective people
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because that imprint stays with them. My colleagues and I started to look
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at these traumatized soldiers, primarily. We actually went back over what had been written before
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The library at the VA I was working Didn't have a single book about war trauma, war neurosis, any of these things
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So I went down to the old Harvard Medical Library, and I dug up a book that was written in 1941
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by a guy by the name of Abram Kardner, who had been working with First World War soldiers
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And he writes about his First World War soldiers back a long time ago
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He writes, these guys suffer from a physiognorosis. Their bodies continue to re-experience the trauma
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trauma, and he says, and the trauma keeps coming back, keeps revisiting them in the form of
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nightmares and flashbacks. They keep reliving what happened back there. They cannot leave
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it behind. And the trauma keeps coming back either as images or as behaviors. That's when
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people behave again as if they are getting raped or getting assaulted, even though they
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are not getting raped or getting assaulted. So what we defined, but people had seen that
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before us, all the way back to well over 100 years, at the core of trauma is that you get stuck
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And that event keeps coming back in terms of images, behaviors, and physical sensations
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So that became at the core of our definition of PTSD. The second piece is that having been constantly bombarded with this horrifying stuff makes
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you preoccupied with, how do I go on with my life? And so you work very hard on avoiding things that make you lose your senses
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And so people avoid it and people suppress it. And people actually learn to not feel things in their bodies
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And they stifle internal sensations, internal feelings. So that's the second piece is on the one side, it's this fight flight keeps going on
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The other thing is you calm yourself down, you try to suppress yourself, you try not to feel
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and so at the end, you don't feel very alive. And the third thing is that you continue to be hyperaroused
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You just keep being bombarded, you keep overreacting to all kinds of things in general
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That's the original definition of PTSD, and that is still the definition
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as you find in the textbook still, But what we discovered is that the whole impact of trauma
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is much larger and it also affects the way you feel about yourself, the way you feel about other people
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the way you are able to notice yourself, the way you experience yourself
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And it has a lot of self distortions and distortions of your body also
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And then over time, we again, we discovered something because these things always have been noted before
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the degree to which when you're traumatized, your body keeps mobilizing itself to fight
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And that you have all kind of immunological abnormalities, you have endocrine abnormalities
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and that really devastates your health, your physical health. At the long range, oftentimes the physical problems
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are longer lasting than the mental problems. The other thing that we discovered
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which is still an area of some controversy in the field, not for me, but for my colleagues who are in power
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is that trauma affects the mind of the brain very differently depending on the age at which you are
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So if something terrible happens to me right now, I have a whole well-developed brain
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and my brain isn't really growing all that much anymore, so I'll get an imprint of the trauma
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that is pretty much superimposed on a relatively well-functioning brain. If you're two, three, or four years old
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your mind and your brain is growing. What various of my research friends have shown
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is that trauma at different ages affects different ways of wiring the brain
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and it gets very complex. And it's like my friend Marty Teicher
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has really shown that trauma at age three changes the brain very differently than trauma at age five
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and trauma at age 14, and that the brain keeps growing and evolving
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And so different events have a different imprint of the brain. That's one aspect
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And the other thing that is terribly important is not only what's happening to you
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but what's happening to your environment. And by and large, as I said before
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if you are really freaked out as a kid, and your parents are there for you
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and they smile at you and say, I'll take care of it, don't worry about it, honey
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I know what to do. Or you have a doctor who really knows what they're doing
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who you can trust. you go like, okay, I can relax now
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because even if I can't take care of it, other people can take care of it for me
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One of the largest mitigating factors against getting traumatized is who is there for you
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at that particular time. When you feel constantly threatened, of course, you don't trust anybody
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but there is a reason to not trust people. The tradition in mental health is to dismiss people
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the reality of people's lives. For example, it's only in the past few years
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that people are beginning to talk about the impact of poverty or the impact of racism or the impact of unemployment
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And people have sort of been labeling people, oh, there's something wrong with you, let me fix you
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But mental health professionals have been very defective in helping people to really come to terms
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with what actually has happened to them and what happening to them right now So a good amount of distrust is very well justified And very likely today if you a traumatized person you don go to a doctor and say
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I was raped when I was four years old, and that's why I come to be treated
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No, people come to be treated because today you blow up at your husband
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And today, you cannot have a safe, satisfactory sexual relationship with your new partner
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And that's why I'm coming into treatment, because the body automatically reacts to certain stimuli
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And most people actually are barely aware or not aware at all that their reactions that
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they're having right now are actually rooted in experiences they've had before
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So if you go to a physician or a mental health practitioner who doesn't understand that
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they're going to try to fix you with drugs or cognitive behavioral treatment to not do
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these crazy things anymore. It usually doesn't work very well because you need to really develop a deep sense of
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this is what happened to me, this is what I'm dealing with. And you need to really acknowledge like, oh my God, that was terrible what happened to
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me and I need to take care of the wounds that I'm carrying inside of myself
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This issue of self-compassion and really knowing that your reactions are understandable and
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are rooted in you getting stuck in the past is a terribly important part of beginning
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to recover from trauma. And as long as you ignore that, you're just a crazy person who has crazy reactions
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The problem with trauma is that it starts off with something that happens to us or that's
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done to us. But that's not where it stops, because it changes your brain
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And from now, that event itself is over, but you continue to react to things as if you're
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in danger. And your brain actually gets changed in a variety of different ways
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And the problem then becomes that you are not able to engage or to learn or to see other
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people's point of view or to coordinate your feelings with your thinking
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And so yet it becomes an internal issue how the trauma continues to fester inside of you
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in a variety of different sensations and perceptions. Yes, there is something wrong with you, but people don't come to see, oh, see me because
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of what happened to them. People come to see me because they feel there is something really wrong with me
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I cannot connect with my kids. I become angry with all my coworkers
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Nobody can stand being around me because I am so reactive. Yes, trauma causes that there is something wrong with you
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And my job as a psychiatrist and all the colleagues and students I have is to help you to feel
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safe in your body and to feel like the trauma is over and that you don't continue to react
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to all kind of things now as if somebody is trying to hit you or rape you
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I think the most important thing to know is that there's a difference between trauma and stress
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As I like to say to people, life sucks a good amount of the time
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We all have jobs and situations that are really unpleasant. But the moment that the situation is over, it's over
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You go on with your life. A trauma happens, and when it's over, your body continues to relive it
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And the core issue is that your body does it. Your endocrine system, your neurohormonal system, your immunological system continues
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to react as if you're back there. So there is something about the development of the mind that gets stopped at that point
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Because the trauma cannot be integrated as, oh yeah, that really sucked
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But it's over now. Trauma makes you think that it's still happening right now
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So the big challenge of treating trauma is how do we help people to live in bodies that feel fundamentally safe
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Where something unpleasant happens to you, you don't react as if you're like, it's in danger
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But you go like, oh, how do I solve this? But when you're traumatized, what's very striking in a whole variety of different brain studies
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what you show is that when you show a non-traumatized person something ambiguous and difficult
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their cognitive brain tries to figure out what's going on. When you show this same stimulus to people who are traumatized, the emotional brain reacts like
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is this dangerous or is this safe? Your brain goes into, is my life in danger
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And that's an emotional reaction. What lights up in the brain is a very different part of the brain
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but then when you have to solve a problem. So you're continuously trying to manage your emotional reactions
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Chapter 2. Shaping Childhood Trauma. People have always noticed that people relive their trauma
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But as I said before, usually people are not aware of it
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Kids are not aware of that they're reliving their having been beaten
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or witnessing domestic violence, and when they go to school, they react in a very angry
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and defiant way with their teachers. Say, oh, this reminds me about my mom and dad fighting, making me scared
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Now, they have an automatic reaction to adults who sound in any way not okay to blow up and
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become very frightened. So they don't make the connection. So what happened when we created this diagnosis of PTSD, we weren't very perceptive
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We're just beginning to see something for the first time. And the most obvious thing in which people relive the trauma is in nightmares
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In nightmares, people see it again, or they experience the event in their dreams
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That is the most obvious, and we could see it. It took us a long time to realize that people also continue to reenact the trauma in their relationships
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That they may relate to their kid the same way they related to people who hurt them as
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little children. And so they don't make that connection. But what allows you to make the connection is when you actually have images of what happened
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back there. But most people don't have visual images. Most people have sensory reactions
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They suddenly feel uptight. They feel nervous, panicky, anxious, enraged. They don't know where it comes from
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After they read books like mine, they know at least where it comes from. some part of your brain that you actually cannot really know because it's beyond cognition
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So, oh, that's why I'm doing that stuff. That's sort of helpful to know
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But most people who are reenacting or replaying the trauma are not aware that they're recreating
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or replaying the trauma. So trauma affects the developing brain different from a well-developed brain
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The research is really very interesting and intriguing about this, and that's the degree
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to which parents hold and modulate kids' traumatic responses. As I said before, when as a kid you get bitten by a dog, it's really very scary and very nasty
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But if your parents pick you up and say, oh, I'm so sorry, let's go and take care of it
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and we'll give you some extra special food, that dog bite doesn't become a big issue
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because the foundation of your safety has not been destroyed. A study I like to quote actually
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and teach people about, is a study that was done in London
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right after the Second World War. Because London was being bombed by the Nazis
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The Brits decided, let's send the kids in London who were being bombed out to the bucolic English countryside
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to live with very nice people. And when the war is over, they'll come back
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and they won't have seen all these dead people and dead corpses and all the bombing
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They'd be much better off. And so after the war, Anna Freud, of all people
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Sigmund Forrest's daughter, and her friend Dorothy Burlingame, did a study of what happened to these kids
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It turned out that the kids who stayed in London with their parents did just fine
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because the safety of kids is determined by how safe they feel with their parents
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Well, the kids who went to the countryside, like Oliver Sacks, who some of your listeners
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may also be a great fan of, like I am, he was shipped to the countryside
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and in his autobiography, Oliver Sacks writes, one of the two most traumatic events in my life
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was being shipped off to the countryside, and I was a really scared and upset kid
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who was primarily preoccupied with the, that my parents are still alive
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but I didn't see them anymore. What trauma also has really taught us
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is the degree to which we are profoundly interconnected and interdependent people
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and we are relational creatures. And as long as our relationships are intact, by and large, we're pretty good with trauma
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Who knows that? The U.S. Marine Corps and the Armed Services, they take a bunch of people who are obviously
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who sometimes escape their own horrible childhood environments and join the military
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and they go into the military. And what does the military do for them
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They create a sense of cohesion, a sense of predictability, a sense of safety
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And so through all these exercises that you do in the army
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you feel very connected with your group. And when you go to war with your group
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you feel very safe that your body is there to protect you
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and that really protects you against getting traumatized. And the very first study I did
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before we knew anything about trauma, was the discovery that the PTSD started for many
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soldiers when they saw their best friend being blown up, because they really had a sense
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of safety and cohesion, because they had a friend, but then that friend got killed, the
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whole world collapsed, and they no longer had the safety that came with the group
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And so what you see with many traumatized people is that they continue to really pull
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towards reconnecting with people who have had similar experiences because when you say
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I was raped and I was raped too, you go like, you know what I'm talking about
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You're special. I can be safe with you as opposed to all these people who have no idea what I'm talking about
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The lingering effect of childhood trauma is that you continue to react to mild stressors
33:20
as if your life is in danger. You tend to become hyper reactive
33:26
People see your reactions as exaggerated. Somebody may irritate you in the supermarket
33:31
and may yell at this person. You may develop road rage. You may have a difficult time putting up
33:39
with misbehavior from your spouse or your kids. And you have exaggerated emotional responses
33:48
The other thing is, it oftentimes is very hard to negotiate intimate relationships
33:54
Negotiating both of our needs, your needs and my needs actually, is a very complex phenomenon
34:02
How do we make compromises? How do we make both of us happy at the same time
34:06
When you have a childhood trauma, that oftentimes becomes very difficult. Very difficult to say, okay, honey
34:12
if that's what you need, I wouldn't want to do that, but I'm fine with you
34:17
if you do that, and these issues of boundaries, and who's responsible for what
34:22
is, becomes a very hard thing to negotiate oftentimes. The big question for me continues to be
34:30
how do you help kids in particular, who have been exposed to enormous amount of violence
34:39
life threats, people who don't pay attention to them, how do you help these kids get a sense of self
34:46
a sense of agency so they can actually make a life for themselves where they can learn
34:53
acquire skills, acquire competencies so they become full-fledged human beings. What the data show is that the long-term effects of child abuse and neglect, which is rampant
35:05
in our country, is the biggest public health issue in America. Let me give you an example
35:11
There are other societies that are much more trauma-savvy than we are
35:15
where there is not an enormous amount of income inequality, where parents actually are helped to take care of their kids
35:22
where health care is universal, where child care is universal. One of these places is Holland, which
35:30
happens to be my native country, which I left when I was 18 years old, and which has become a very nice place
35:36
So in a culture like that, that really looks at what are the antecedents for getting people
35:42
to be dysfunctional. They do all these things to help people to take care of their kids
35:47
And so in the Netherlands right now, the incarceration rate is 58 per 100,000 people
35:54
In the US, it's 950 per 100,000 people. So the big issue is a political issue
36:02
How do we rearrange our society to really know about trauma and to really do all the things that are necessary
36:09
so that people who grow up under extreme adverse conditions can develop a brain and a mind that can help them
36:16
to become full-fledged members of society instead of on the edge as drug addicts and disabled people
36:25
or people who need to go to jail. That's our big issue, and that's the big challenge that we have
36:33
Chapter 3, how to treat trauma. I was raised in the mainstream culture as a professor, prestigious institutions
36:45
And what's mainstream culture? The culture we live in is that when you feel bad, you take a swig of alcohol
36:53
Or you take a swig of something to make that feeling go away. I call our medical culture right now a post-alcoholic culture where if you feel bad, you take something to make that feeling go away
37:06
And it turned out that taking something didn't make the feelings go away
37:11
but wriggling your fingers in front of people eyes as you think about the trauma made the trauma go away And I go like wow this is really interesting When I first got to see trauma and got intrigued with it
37:23
I looked at the treatments that we have. And so I did the first study on Prozac for PTSD
37:30
the first study for Zoloft for PTSD, and a number of other conventional drugs
37:35
What we found is that it didn't work very well. And we published those data in prestigious medical journals
37:41
And people said, boy, Van der Kolk is a great psychopharmacology researcher
37:45
But our results showed that they don't work very well. Somehow, psychiatry never got the message that said
37:53
no, drugs are not particularly helpful. And the VA still spends billions of dollars on drugs that don't work
38:00
They were unable to go through a trajectory that I and most of my colleagues went through
38:06
like, okay, if it doesn't work, let's do, see what else can work
38:10
People always ask me, how can you put up with all this misery that you hear
38:15
And I agree, it's not easy. But one of the things that helps you is to really understand that people do the best they can
38:23
That somebody who is enraged in response to a minor thing is not becoming enraged because they just are unpleasant, difficult people who don't try
38:33
No, they try. People try to survive. Every person tries to have the best possible life they can have
38:41
And sometimes it goes really wrong. But for example, when you're a little kid and you don't feel like anybody's there to
38:49
help you when you become distressed, you may learn that banging your head against the wall
38:54
or stabbing yourself, or burning yourself, or starving yourself may make you feel better
39:00
And so what you discover is that people do all kinds of things that seem pretty weird
39:06
sometimes on the surface to protect themselves. There was a moment in sort of the history of our field that was particularly poignant
39:14
in this regard. Vince Felletti, who is the internist who did the ACE study, the Adverse Childhood Experiences
39:21
study, had a very important experience that he shared with all of us, which makes perfect
39:26
sense to me. He had a weight loss program, and that's all he did. He was very proud of his weight loss program
39:32
And then one day, a woman came to his office who had lost something like 150 pounds or
39:38
something in the course of the weight loss program. And she came back three months later, and she had regained almost all of her weight
39:47
He said, I didn't know people could gain so much weight in such a short period
39:51
What happened to you? And she says, you know, Dr. Fellaini, your weight loss program was terrific
39:57
And I became svelte, and people's reaction to me completely changed. So after my last visit to you, when you complimented me about how well I was doing, I went back
40:07
to my office and one of my co-workers said, boy, you look really hot
40:11
Would you like to go on a date tonight? And the moment he said that, I started to eat
40:17
And I haven't stopped eating because what I realized is overweight is overlooked
40:23
And the way I dealt with my childhood sexual abuse is to make myself grossly obese so nobody
40:29
would have an interest in me in a sexual way. So that was one of these openings
40:34
You get to see that some of the behaviors that we may condemn or be upset about actually
40:41
are behaviors that start off trying to take care of yourself. That actually is also true for drug abuse
40:48
People say, it's a biological illness, but it's not so simple. But if I say to you right now, oh, I have a little needle with some heroin in it
40:58
you feel good, would you like to try it?" You'd say, you're crazy. I'm not going to take heroin
41:03
But if you are in despair and you don't know if you're going to make it through the night
41:08
and I say, I have a little drug here that can help you make it through the night, you're like
41:11
please, please give it to me. That's where drug addiction comes from. That's also to a large degree
41:16
where opioid epidemic comes from. It's also the stuff being made available to people. But, you know
41:22
Now, among my colleagues who have privileged lives, they don't become drug addicts because
41:32
they have good lives. They don't need to cure something in terms of how upset they are
41:38
But since time immemorial, people take drugs in order to deal with unbearable sensations
41:46
The military had a huge drug problem during the Vietnam War because people take these
41:51
drugs in order not to feel their pain. If we really want to take care of drug abuse
41:57
we really have to look at social situations and circumstances that make people feel desperate
42:03
and hopeless. Very good psychotherapy, not to fix people, but helping people to know what they're feeling
42:16
find ways in which to cope with those feelings was really quite helpful
42:20
But it's very clear is that being in a relationship where people can hear you
42:26
where you can talk about how badly you feel, where you can talk about your guilt
42:31
and where you can start opening up where these feelings come from
42:35
how old these feelings are, and how you develop these feelings in response to particular things that happened to you
42:42
that was actually quite helpful. Finding words for your internal experience, which is oftentimes very difficult for traumatized people
42:50
They actually have impairment of being able to know themselves, being able to discover who they are
42:56
and how they got these reactions is very helpful. And then for me, the opening to a new world came
43:05
when some people in my clinic started to do something very strange, something called EMDR
43:13
Eye movement desensitization and reprocessing. A technique where you ask people to call up the memory
43:21
of what you saw back then, what you heard back then, what you felt back then
43:26
but you don't ask people to talk about it. Because the moment you start talking about something
43:31
you get more preoccupied whether the person you're talking to understands you, likes you, is disgusted with you
43:38
So it becomes an interpersonal process. This, you ask people to just feel it and notice it
43:45
And then what you do is that you ask people to follow your fingers as you move your fingers
43:51
from side to side in front of their eyes. And my first reaction with my students
43:57
and junior colleagues who do it is like, man, stop this crazy nonsense
44:01
This is a crazy method. And then I got to see some of the results
44:05
I go like, wow, this is interesting. This is different. And so I did a study funded by NIH
44:14
funded because people saw me as a very good psychopharmacologist, not a guy who had gone off the deep end
44:20
doing crazy methods like EMDR. And everybody expected that we'd find that the drugs are much better than EMDR
44:27
And what we found is that this crazy eye movement decentralization had amazing effects on people being able to let go of what happened Say say yes that what happened to me and it happened a long time ago
44:40
It's not happening right now. That was the first time that I saw a non-conventional technique have a very profound effect
44:48
And that really had a very deep effect on my thinking about treatment of trauma
44:54
And of course, my colleague said, PESOL has gone off the deep end
44:58
And the data on EMDR was still better than any data of the treatment outcome that anybody
45:04
had studied. But people didn't want to go there because it's such a crazy method
45:08
So I tried to get money to study what those eye movements do to the brain
45:13
It took us about 15 years to collect money from other sources to finally do that study
45:19
where we were able to show that you move your eyes from side to side, that you actually
45:24
We change brain circuits that changes the executive function of the brain, the default
45:30
mode network of the brain, and the salience network of the brain
45:34
So what we discovered with all the other things that happened in neuroscience is that this
45:39
strange eye movement that sounds so bizarre actually changed the circuitry of the brain
45:45
to interpret your current reality from a different angle. What I discovered at this point is that our conventional way of thinking about it is not
45:55
working, but strange stuff works. And then a bunch of yoga teachers come to talk to me and say, we do yoga for PTSD and
46:06
seems to help people. And that made sense to me on some level
46:11
Maybe if you do yoga, yoga can open up your relationship to your body, to your physical self
46:18
how to breathe calmly, you learn to pay attention to yourself, you get to see how different movements
46:23
and different postures affect you. And so you form a deep relationship
46:27
to your internal sensory system. Trauma is carried in the sensations of your body
46:34
in heartbreak and gut wrench. And that you have been able to see in the brain
46:39
is that your connection with your body becomes weaker and weaker so you don't feel your body anymore
46:46
so you don't feel your pain anymore. The problem is that if you don't feel your pain anymore, you don't feel your pleasure
46:52
anymore either. I was reading an extraordinary case report of somebody who lost all sensations in their
46:59
skin, in their bodies. And it's a very, very rare thing to happen to people
47:04
And what people discovered is if you cannot have a sensation in your skin, you cannot
47:10
have a sensation of pleasure. An association of pleasure is carried by the corpuscles in our skin
47:18
So we need to get pleasurable sensations coming from our body to get a sense of pleasure and joy
47:23
And that was really interesting to me also because traumatized people, and that's left
47:28
out of the definition, have a tremendous problem experiencing pleasure and joy
47:34
I applied a number of times to study that. And at the end, we did get funded to do the very first yoga study for PTSD
47:42
And what turned out is that the way the data looked to me, yoga at the end was a more effective
47:49
treatment for PTSD than any of the drugs we had studied. And we did a number of yoga studies
47:56
We published them in respected medical journals. But I've yet to see a psychopharmacology clinic being transformed into a yoga studio
48:05
So even though it's pretty clear that needing to feel safe in your body and to own your body
48:11
and to feel all the sensations in your body is a critical aspect of healing from PTSD
48:20
The next thing that we studied was theater and movement. And it turns out that playing different roles in your body helps you to feel that your body
48:31
can feel differently depending on how you organize your relationship to yourself
48:36
So I live in the Berkshires, and we have a great program here called Shakespeare in the
48:42
Courts, where if you're a juvenile delinquent in this country, you have a 50% chance that
48:47
the judge will condemn you to become a Shakespearean actor. That's civilization
48:53
And the Shakespeare program is enormously helpful because it helps people to feel their
48:59
bodies, and to feel what it feels like to be a king, and to feel like to be a warrior
49:04
and to feel what it feels like to feel you. And you get to really have a deep experience of yourself in different possibilities
49:13
We learned that you can actually put electrodes on your skull, and you can harvest your brain
49:19
waves and project them on a computer screen, and then you can program the computer screen
49:25
So that when you make brainwaves that help you to be calm and focused, the computer game
49:31
is working. And if your brain makes waves that don't do that, there's no computer game
49:37
So your brain wants to play the computer game. But the moment you develop brainwaves that are not helpful to you, the screen goes blank
49:46
So your brain sort of wants to do the right thing. And you can actually train people to make the right brainwaves
49:53
And that's another piece of research that I feel very proud of, because it's very hard
49:57
to find funding for it. But we really showed that we can change people's brain and brain connections by playing computer
50:04
brains, games with your own brain, which is another important project that I'm working
50:09
on and trying to implement in various communities. And also, I did a study of foster care children who are extremely out of control kids, who
50:20
who have no prognosis to probably ever function very well because they're just too disorganized and too hurt
50:27
And we did very well with Neurofeedback to help them to calm their brains down
50:32
and to learn and to be in classrooms and to have friends
50:36
So there's all these things that at this point are still called alternatives, that unless we go there
50:43
our patients continue to get stuck on not getting better. You have to keep looking
50:50
About 15 years ago, two guys came to talk to me, Rick Doblin and Michael Mithoffer
50:57
and they said, Bessel, you know a lot about trauma. What do you think about this idea
51:02
We are thinking about psychedelics. What do you think about psychedelics for trauma
51:07
And I go like, wow, that you're speaking from my heart. Because, of course, I'm a child of the 60s
51:14
And like everybody else who I know who grew up with me, we dabbled in LSD and psychedelic substances
51:20
I have a number of friends who are very well-known scientists actually, and I have asked all of
51:28
my friends, did you top acid as a college student also? And everyone of my friends said, sure did
51:35
And I said, so how do you think it has affected your career
51:40
And everyone of my friends says, you know, I think I've become the creative scientist
51:46
that I am because I took these substances because it allowed me to see that the reality that I was raised in the reality that I see is a very small part of the overall reality that I is
52:01
Those sort of answers make me feel very curious because one thing that all of us who know
52:07
about trauma know is that when you get traumatized, you start living in a very narrow reality
52:13
The reality of the war in Iraq, the reality of your incest, that colors everything you do
52:19
And so you become intellectually and emotionally quite a constricted person because you are
52:24
always afraid to get hurt and you still feel like I'm about to get hurt again
52:29
So that becomes your world. I said to them, wouldn't it be great if we could do psychedelic substances to see if
52:35
these substances can open up people's minds and to see that the reality that they live
52:40
in is just a small part of the reality that there is
52:44
And then I said, don't do it. You're crazy. These drugs are illegal
52:51
I knew a whole bunch of people who did LSD and psilocybin research back when I was young
52:57
It helps me around a little bit because I saw that revolution back then
53:01
I had Timothy Leary's office at Harvard for a period of time
53:06
I know what happened to all these guys. I said to Rick and Michael, don't do it
53:11
It will destroy your career. You'll never get permission. And they said, thank you very much for your opinion
53:17
We'll try it anyway. And they tried anyway. And through great challenges and lawsuits, et cetera
53:24
they got permission to do a study of MDMA for trauma. And it worked out pretty well
53:29
And they got permission to do a second study again. Very hard to do. And they did very well
53:34
And then, Rick Doblin was able to collect a large amount of money, largely from Silicon
53:41
Valley people, to do a very large and extremely expensive study of MDMA, also known as Ecstasy
53:48
or MOLLE. When that happened, they asked me if I wanted to be the principal investigator of one of
53:54
the sites, the sites in Boston. And I said, boy, I admire you so much for having been able to get the study of the ground
54:02
I would love to see what it does. But the main reason why I want to be involved in the study
54:07
is to warn people not to get carried away because last time people got carried away
54:12
and the whole world collapsed. And this time we need to be extremely careful
54:16
so that if we find something, we do it very carefully and we don't get the backlash
54:22
We did the study. Lots of different sites around the US, one in Israel, one in Canada
54:27
We saw remarkable results. The paper was published in Nature Medicine, a very prestigious medical journal, that shows
54:35
that the MDMA causes a very, very substantial drop in PTSD, probably more than just about
54:43
anything else we have studied. Although I'm not 100% sure of that, but very dramatic
54:49
And then what comes up for me is, yeah, the PTSD score is interesting, but what we see
54:55
in the people we work with is much more profound than just PTSD
55:01
So let me tell you how the study is set up. People apply to be in the study
55:04
It's a very tough study to be in. It takes about nine months to do it
55:09
You come in, you get tested up the zoo, you go off all your medications, you do a lot
55:15
of tests, you have a number of preparatory sessions, and then finally, after all the
55:19
preparation, you have a whole day of taking ecstasy while you lie on the bed in the eye
55:27
shade with two therapists in your room for eight hours and then stuff happens, which
55:32
I'll talk about in a second. You sort of calm down from the experience, you stay overnight
55:37
The next day we interview people again, we interview people several times in between
55:42
You have your next experience a month later, a number of sessions in between, and you have
55:47
your next experience again. It's not surprising that our control group, where people get an inactive substance, also
55:54
do very well because people get very intensive psychotherapy alongside the drug
56:00
So half people get a drug, half people don't get a drug. But what we see in the people who get the drug is amazing
56:06
What we see is that people are able to go to places they have never felt safe to go to
56:13
This is not a picnic. People go and see their rape. They see their molestation, they see the horrible things that happened to them
56:23
But what MDMA does, it allows people to see themselves with compassion
56:28
And rather than blaming themselves or getting freaked out, they go like, oh yeah, that's
56:34
what happened to me back then. It was horrible. But what we see is a profound transformation of the personality, not just PTSD
56:44
And so I was very lucky that the organization asked me to yze what's called the secondary
56:50
data, which I'm doing right now. And the secondary data are, wow, they're just mana for my soul
57:00
Because it brings the mind back into psychiatry. After people take MDMA, they're able to talk about themselves
57:08
They're able to have compassion for themselves. much better able to say, this is what's going on with me
57:16
So all these measures we have about self perception and self awareness just shoot up and people become owners of their own lives
57:27
And they're able to say, yes, this is what happened to me, but it's over
57:31
And then we look at the whole issue of executive functioning, being able to make plans, being able to attune to other people
57:40
Being able to feel alive, big changes. People come to life. And when people are in difficult relationships
57:48
they say, honey, that's your problem. That's not my problem. And people sometimes leave abusive relationship
57:56
and they say, I don't need this abusive relationship. I'm okay. I can take care of myself
58:02
And you see very profound existential transformations in people. And I think that's really at the end holds the promise
58:11
that people can leave the trauma behind and not say I'm a veteran who still screwed up
58:16
Yes, I was a veteran back then, I was 18 years old, but today I'm 23 years old or 48 years old or 60
58:25
and I'm a plumber and an artrician, movie maker, whatever. And that's part of my experience
58:30
but it doesn't define who I am anymore. It's remarkable. so
58:45
let's go
59:02
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