As supplement use increases, so do cases of liver failure linked to them
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May 28, 2025
Healthy life hacks: exercise, eat well and take supplements — right? Turns out, supplements could be putting your health at risk.
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We all know the basic tenets of living a healthy lifestyle, exercising, eating healthy, and for many, taking vitamins and supplements
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But it turns out some supplements built to help you live longer could actually be putting your life at risk
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It all comes down to your liver, the organ responsible for filtering harmful substances from the blood
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And while your liver works hard to do that, it can be overwhelmed by certain drugs or supplements
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leading to something called drug-induced liver injury, also known as toxic hepatitis
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Acetaminophen, more commonly known under the brand name Tylenol, is a good example
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It is one of the most common causes of toxic hepatitis. But as more people use supplements, more cases are popping up
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According to a 2024 survey by the Council for Responsible Nutrition, as many as three out of four or 75 percent of American adults take some form of supplement
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whether it be herbal or dietary. And nearly four in five say they would rather take supplements
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than prescription or over-the-counter medications. Comparatively, the CDC's most recent study done on
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the subject shows that between 2017 and 2018 just a little over half of adults 20 and older had used to supplement in the last 30 days A study published in the medical journal Liver Transplantation in 2022 found the number of patients added to the wait list
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for a transplant because of supplement-related liver failure increased eightfold, from 2.9% in 1995
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to 24.1% in 2020. Experts say it's hard to figure out what the exact culprit is
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A 2017 study by the American Association for the study of liver diseases found 20% of liver toxicity cases in the United States could
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be linked to dietary or herbal supplements. But since the supplements contain multiple ingredients
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they're not sure which one or ones are to blame. However, there are some you can make sure to look
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out for. A study published last year out of the University of Michigan found six common ingredients
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can definitively be tied to toxic hepatitis, turmeric, green tea extract, ashwagandha
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garcinia, cambogia, red yeast rice, and black cohosh. The study's authors said about 15 million
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Americans take at least one of those supplements. Since supplements are not regulated in the same
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way medications are, you cannot always be sure what you're getting or if the dosage is correct
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