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artificial sweeteners are pretty
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polarizing some people swear by them and
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others are convinced they're the worst
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thing for your health
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what does the research tell us about
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let's talk about that
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how's it going guys my name's richie
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kirwan and today we're going to talk all
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about artificial sweeteners what they
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are why they're so popular what are
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their benefits and what negative effects
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they might have as always i want to
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point out that i'm not recommending you
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use a particular sweetener what i am
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going to do is help you understand what
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the research says about their pros and
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cons so you can make a better more
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informed decision about using them or
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not let's get started first off what
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even is a sweetener basically it's a
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food additive that gives a sweet taste
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to food but has far fewer calories or
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virtually none compared to sugar you
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might ask why would people want to
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replace sugar in their diet there's
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nothing inherently wrong with sugar
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itself but added sugars in food can
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contribute to people taking in a lot
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more calories than they normally would
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you can add a lot of sugar to food
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without increasing its volume a huge
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amount which means it can make food very
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calorie dense and sugar also improves
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the texture and moisture content of food
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as well which makes them sweeter and a
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lot more enjoyable that makes food more
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appealing and a lot easier to overeat
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and that's really the main issue with
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added sugars they make overeating a lot
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more likely which makes weight gain a
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lot more likely to now don't get me
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wrong i'm not saying sugars cause
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obesity because sugar is often found in
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a lot of other foods together with fat
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adding to that calorie density if you
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can replace sugar with something that
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still tastes sweet so it still makes
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food appealing to humans because we
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naturally have a sweet tooth without
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adding all of the calories of sugar you
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can potentially help people to lower
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their total calorie intake and either
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lose weight or help them maintain weight
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loss because of this artificial
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sweeteners have become a multi-million
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dollar industry at this point i also
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need to talk about the elephant in the
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room the word artificial in artificial
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sweeteners really does put some people
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off using them this is because of
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something called the naturalistic
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fallacy the naturalistic fallacy is the
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idea that anything that is natural is
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inherently good and anything that is
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unnatural or artificial is inherently
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bad this is terrible logic let me give
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you an example of that
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one of the most toxic substances known
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to mankind is botulinum toxin which is
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100 natural on the other hand there are
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a lot of artificially produced compounds
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which are incredibly beneficial to human
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health for example many of the new
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varieties of antibiotics which save
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people's lives or artificially
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synthesize vitamin d which can cure
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deficiencies saying natural is good and
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artificial bad is overly simplistic
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thinking because of that sometimes
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people use other words to describe
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artificial sweeteners and say things
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like non-nutritive sweeteners or
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non-caloric sweeteners i should also
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point out that there is another group of
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sugar substitutes known as polyols or
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sugar alcohols these include such common
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sweeteners as sorbitol mannitol
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erythritol xylitol which many of you
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probably have heard of while these
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sweeteners are often considered to be
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natural because they're found in nature
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many of them are produced industrially
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by hydrogenation of sugars for example
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which shouldn't be confused with
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hydrogenation of oils or by fermentation
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the difference between sugar alcohols
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and non-nutritive sweeteners is that
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sugar alcohols do provide some calories
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but they are generally much lower than
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the calories found in sugar usually
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between 0.2 and 2.5 calories per gram
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compared with 4 calories per gram in
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sugar unfortunately that's all i'm going
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to say about sugar alcohols today
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instead i'm going to talk about
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non-nutritive sweeteners some examples
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of which include sucralose often known
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by its trade name splenda
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ace sulfate and potassium or acethane k
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otherwise known as ace k and stevial
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gykoside which many of you will probably
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know as the natural sweetener stevia or
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also mugracide which is naturally found
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in monk fruit just to give you a little
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idea of the difference between some
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non-nutritive sweeteners
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sucralose is the world's most commonly
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used artificial sweetener and is about
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300 to 600 times sweeter than table
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it's heat stable and is often used in
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cooked food products the food and drug
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administration or fda states that there
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are about 110 different studies which
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were used to confirm its safety as a
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food additive aspartame is about 180 to
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200 times sweeter than sugar and is not
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heat stable so it's not suitable for
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cooked foods or baked goods according to
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the fda there are over 100 safety trials
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that confirm the safety of aspartame ace
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k is about 200 times sweeter than sugar
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and is heat stable so again it's used in
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cooked foods according to the fda there
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are over 90 safety trials confirming the
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safety of ace k as for the natural
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stevial glycosides which are an extract
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from the stevia plant are about 250 to
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300 times sweeter than sugar
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each sweetener also has an adi or an
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acceptable daily intake an adi is
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calculated based on how much of a
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substance a person can consume every day
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without any health effects and has a
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huge safety margin built into it as well
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that means if you consume something up
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to its adi you are still nowhere near
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consuming enough to have a negative
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effect on your health for example the
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adi for sucralose is five milligrams per
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kilogram of body weight per day for 70
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kilogram person that's 350 milligrams
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per day meaning you'd need to use over
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26 individual serving packages of super
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loss a day just to reach the adi and
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that's still nowhere near the amount
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that would be harmful other sweeteners
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have similarly safe adis now as you can
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see there are a lot of different
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sweeteners on the market all of which
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can have different properties and
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effects that means that you can't assume
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that the effects of one sweetener would
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be the same as another
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don't some sweeteners contain methanol
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this is another issue related to
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aspartame i already mentioned that when
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aspartame is broken down in the body it
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forms aspartic acid and phenylalanine
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it also releases a molecule of methanol
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which indeed is toxic
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however the amount of methanol that's
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released from a moderate intake of
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aspartame is actually far less than the
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methanol we normally get from fruit and
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vegetables that we eat daily which occur
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totally naturally there's a really
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important saying in toxicology the dose
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makes the poison this means that
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something can only have a toxic effect
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when its dose is high enough a good
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example of this is vitamin d if you
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don't get enough vitamin d you can
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suffer from a lot of healthy juice but
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if you get too much for example by
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taking excessive supplements it can have
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toxic effects in the body don't forget
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the dose makes the poison what about
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this is another common question i hear
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about sweeteners oftentimes when a study
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says something really bad about a food
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or a nutrient if someone hears that it
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tends to stick in their memory and
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that's why a lot of inaccurate
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information tends to persist as
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so-called common knowledge there have
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been a number of studies that have shown
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that high intakes of aspartame can cause
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an increase in tumors now that sounds
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really scary until you read those
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studies firstly these studies were
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carried out in rats oil experiments in
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rats are really important for human
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health studies as well
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oftentimes something that happens in
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rats or mice doesn't happen the same way
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in humans we are different animals with
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different metabolisms and those
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metabolisms react differently to
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different foods the classic example of
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this is chocolate chocolate is quite
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possibly one of the most popular sweet
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snacks on earth and dark chocolate is
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even known to have health benefits but
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if you give chocolate to a dog it will
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why because dogs metabolize chocolate
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differently some of these studies were
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also carried out in the prenatal stage
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which means that female mice were
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treated with aspartame while they were
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pregnant and the offspring were then fed
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aspartame for the rest of their lives
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you can't compare giving a substance to
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a fetus in utero while it's in the womb
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with taking lower doses of it as a fully
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formed human being finally these studies
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also used incredibly high doses of
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aspartame which is perfectly normal for
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a toxicity study by the way the adi for
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aspartame is 50 milligrams per kilogram
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of body weight and some of these studies
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used up to 5 000 milligrams per kilogram
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that's not a dose of aspartame that a
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human would ever consume normally any
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time a substance is associated with a
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very serious condition such as cancer we
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need to take that seriously and that's
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why we perform all of these scientific
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trials to determine whether it's safe or
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not as i mentioned aspartame has already
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been deemed to be safe by the fda in
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over 100 scientific trials but because
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those my studies were sensationalized by
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the media they're forever burned into
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the memory of the population and this is
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why people are continuously suspicious
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of aspartame in science we have to base
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our judgments on all of the available
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information that we have and that
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information does change over time as we
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perform more studies at the moment the
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consensus of studies is that there
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doesn't seem to be a link between
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artificial sweetener consumption and
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cancer in humans now i'm a scientist and
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that means i have to change my mind when
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i'm presented with new evidence so if
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some new evidence comes to light in the
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coming years that makes me change my
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opinion about artificial sweeteners
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aren't they just as bad for your blood
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sugar as real sugar this idea gets
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let me clarify one thing straight off
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non-nutritive sweeteners can't directly
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cause your blood sugar to rise because
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they don't contain any sugar themselves
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no sugar in the sweetener
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not entering your bloodstream
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no increase in blood sugar a different
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side of that coin is overall blood sugar
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control there is evidence that the sweet
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taste alone without any sugar or
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calories can cause insulin levels to
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rise a small amount without food even
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entering the stomach in some people this
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is called the cephalic phase insulin
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response or cpir and it happens in
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response to the expectation
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of food it's also a considerably smaller
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rise in insulin compared to the second
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phase in response to sugar that said the
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cpir is not necessarily a negative
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effect what would be worrying is if
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non-nutritive sweeteners had an effect
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on blood sugar control but a recent
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meta-analysis that's a study that looks
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at the combined results of a number of
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similar studies found that sweeteners
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including aspartame saccharin
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steviosides and sucralose did not
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elevate blood glucose levels what about
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causing you to want to eat more sweet
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well there was a recent study that asked
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this question and found that
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artificially sweetened drinks actually
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reduced desire for sweet food and drinks
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immediately after consuming them now
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there is a possibility that using
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sweeteners very often might make you
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want more sweets in general but we don't
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have any hard evidence to say that this
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actually happens we do however have good
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evidence from multiple randomized
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control trials using different types of
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sweeteners showing artificial sweeteners
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don't cause people to overeat calories
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in general it just doesn't happen
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despite all the rumors you may have
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heard ah and here's my favorite
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don't they cause weight gain
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this idea comes from observational
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studies just to give you an idea
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observational studies are where you take
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a group of people and measure something
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about them like their height or weight
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or health status but don't actually do
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an experiment or intervention with them
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these early studies found that people
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who use non-nutritive sweeteners were
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more likely to be overweight here's the
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thing though this is likely an example
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of something called reverse causation
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for example when people who have
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overweight or obesity start using
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non-nutritive sweeteners to help lose
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weight this produces a false association
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between sweetener intake and obesity
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however there is a lot of data from
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well-controlled studies that show that
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sweeteners do help with weight loss
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efforts they do this in two ways one by
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replacing the calories that would
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normally be found in sugar-sweetened
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foods especially sugary drinks and two
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by helping people to manage hunger or
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cravings for sweet foods here's the
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many people including myself
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love sweet foods and the food industry
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figured that out a long time ago that's
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why added sugars are found in so many
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different foods these days it's cheap
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and it causes people to eat more which
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means people are more likely to gain
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weight if we can satisfy people's desire
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for sweet food without adding all of the
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calories of added sugars it makes it
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more likely that people will eat less
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unless they decide to compensate later
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to congratulate themselves for having
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one sugar-free product in the day you
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might think that sounds silly but that's
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exactly how humans think finally for
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anyone who likes to think that
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artificial sweeteners are as bad as
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sugar think of it like this
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if someone drinks a lot of sugary drinks
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and that causes them to gain weight and
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develop conditions like diabetes or
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fatty liver or high blood pressure
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simply switching to artificially
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sweetened drinks might be an incredibly
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easy way to help them lose body fat and
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improve their health in that situation
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using sugar and having a higher risk of
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developing a load of conditions
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associated with calorie excess or
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using a sweetener which has no
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definitive associations with any
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negative health effects like i said i'm
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not here to tell anyone to use
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artificial sweeteners or not whatever
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you do i just rather you make your
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decision from an informed place so did
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this answer your sweetener questions as
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always if you have any more let me know
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in the comments below and remember to
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like and subscribe to the my protein
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youtube channel for even more great
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evidence-based nutrition information