0:01
Hello and welcome. You're probably here
0:03
for a very specific reason. You want to
0:05
know how to reconstitute trespide and we
0:08
are absolutely going to walk through
0:09
that process. But maybe more
0:11
importantly, we're going to uncover some
0:13
really critical warnings that anyone
0:14
asking this question needs to hear. So
0:17
yeah, you're searching for a direct
0:19
answer to that exact question and I
0:20
promise we will get to it. But to really
0:23
understand the how, we've got to cover
0:24
the what and you know the why first. So
0:27
why does tears of piety even come as a
0:30
powder in the first place? Well, it's
0:32
because of a cool process called
0:33
lipoilization, which is basically just a
0:35
fancy word for freeze drying. This
0:37
technique sucks all the water out, which
0:39
makes the medication super stable and
0:41
gives it a way longer shelf life. But of
0:43
course, before you can use it, it has to
0:44
be turned back into a liquid, and that's
0:46
the whole reconstitution process. To do
0:49
this, you need a pretty standard set of
0:51
gear. The vial of the powdered tears of
0:53
patide, a sterile solvent like bacteria
0:55
static water, syringes, alcohol swabs,
0:58
and of course, a really clean workspace.
1:01
Seems straightforward enough, right?
1:03
Well, hold on before we dive any deeper
1:05
into the howto part. We really need to
1:07
pump the brakes. There is an absolutely
1:10
crucial piece of information here that
1:12
pretty much changes the entire context
1:14
of this question. And it all boils down
1:16
to this one simple question. What kind
1:20
of turppetide are you actually using?
1:22
Because, and this is so important, not
1:25
all tzepide is the same. And the answer
1:28
is critical for your safety. This right
1:30
here is probably the most important
1:32
thing we'll talk about today. You've got
1:34
two main types of tzepide. On one side,
1:37
you have the official FDA approved
1:39
versions, Mjaro and Zeppbound. They're
1:42
made by Eli Liy and come ready to go. No
1:44
mixing required. But on the other side,
1:46
you have something called compounded
1:48
tzepide. And the huge glaring difference
1:50
is that these compounded versions have
1:52
not been looked at by the FDA for
1:54
safety, quality, or if they even work.
1:57
And look, this isn't just me saying
1:59
this. Eli Liy, the one and only company
2:01
that makes the FDA approved drug, has
2:03
been putting out these really stark
2:05
warnings about the unapproved versions.
2:07
They sent out this official notice
2:09
spelling out their safety concerns. And
2:12
the letter, it does not mince words. It
2:14
says that the sale of this unapproved,
2:16
untested, compounded tzepide is, and I'm
2:19
quoting here, putting patients across
2:21
Georgia at risk. That really just
2:24
hammers home how serious this is. So,
2:27
when we actually break down what those
2:29
risks are, the picture gets even clearer
2:32
and frankly a little scary. We're
2:35
talking about zero FDA review, the
2:37
potential for dangerous contamination,
2:39
getting the wrong dose, and even having
2:41
untested stuff like B vitamins thrown
2:43
in, which some compounders do with
2:45
absolutely no clinical evidence. Now,
2:48
you might be thinking, well, if it's so
2:50
risky, how was this ever allowed? And
2:53
that's a fair question. For a while, the
2:55
official FDA approved drugs were on the
2:58
drug shortage list. And when there's a
3:00
shortage, the law temporarily allows for
3:02
some compounding. But that situation has
3:05
changed. The shortage is over. This
3:08
timeline shows you exactly how that
3:10
legal landscape shifted. Back in late
3:12
2024, the FDA officially said the
3:14
shortage was over. Now, some
3:16
compoundingies tried to fight this, but
3:18
in early 2025, a US district court shut
3:21
them down. So, the key takeaway here is
3:23
that legal loophole for mass compounding
3:25
these drugs. It's gone. Okay, before we
3:28
go any further, I need to be absolutely
3:29
crystal clear on this. This explainer is
3:32
for educational purposes only. This is
3:34
not medical advice. You have to have to
3:36
consult with a qualified healthcare
3:38
professional before you make any
3:39
decisions about your medication. Please.
3:42
All right. Now that we have all of that
3:44
really critical safety and legal context
3:46
out of the way, let's get back to the
3:48
mechanics of the process itself. Looking
3:50
at this purely as an educational
3:52
overview. So, the process is pretty
3:55
methodical. Step one is all about
3:57
sanitation. Clean hands, a clean
4:00
surface, and swabbing that vial stopper.
4:02
Step two is carefully measuring out the
4:04
correct amount of sterile water. For
4:06
step three, you inject that water
4:08
slowly, aiming it against the side of
4:10
the vial so it doesn't get all foamy.
4:12
And finally, step four, you just gently
4:15
mix it by swirling or rolling it. You
4:17
never ever shake it until the powder is
4:19
completely gone. And here it is, the
4:21
specific answer a lot of you probably
4:24
came here for. According to the guides
4:26
out there, for a 30 mgram vial of tears
4:28
ofatide, you would typically use 3 milll
4:31
of sterile water. Now, while that gives
4:33
you the direct ratio, just remember this
4:35
applies to those unapproved products
4:37
we've been talking so much about. Okay,
4:40
before we get to our final takeaways
4:41
from all this, we're just going to take
4:42
a quick break for a word from our
4:44
sponsor. For those of you who might be
4:47
conducting legitimate laboratory
4:48
research, our partner Apollo Peptide
4:50
Sciences is a really trusted source for
4:52
highquality research-grade peptides. And
4:55
I need to be perfectly clear here, these
4:57
are sold for research purposes only and
4:59
are not for human consumption. So for
5:01
those specific research needs, you can
5:02
use the code FDN15 to get 15% off. We've
5:06
got the link for you in the description.
5:08
So let's bring all this together. What
5:11
is your final takeaway? Because really,
5:14
when it comes down to your health,
5:16
knowledge is the absolute foundation of
5:18
safety. Okay, let's recap. The physical
5:22
act of reconstituting, yeah, it's a
5:25
pretty straightforward mixing process,
5:26
but, and this is the huge but, it's a
5:29
process that's only needed for non-FDA
5:31
approved compounded versions. We've seen
5:34
that the official manufacturer and the
5:35
regulators have put out serious safety
5:37
warnings about this stuff. And that
5:38
legal loophole that allowed it to
5:40
happen, it's closed. The bottom line is
5:42
this. Always always verify the source
5:45
and the approval status of any
5:46
medication you're using. So you see the
5:49
really crucial point here is that we
5:51
started with the question of how to mix
5:53
this medication. But after everything
5:55
we've looked at the more important
5:57
question, the one that really matters is
5:59
whether you should be using a version
6:01
that makes you mix it at all. If you
6:03
want to do your own research, and I
6:05
really encourage you to, you can see all
6:07
the documents for yourself. We have
6:09
linked every single source we used to
6:11
create this explainer right down in the
6:12
description below. Hey, if you found
6:14
this explainer valuable, please hit that
6:16
like button. It really helps us reach
6:18
more people with this kind of important
6:19
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